Cost analysis · Tirzepatide

What a year of compounded tirzepatide actually costs

A year of compounded tirzepatide costs between $1,668 and $8,964 depending on which program you pick, and the gap between those two numbers is larger than most people's annual grocery bill. This is where that spread comes from, and which parts of it you can actually control.

The spread, computed

Across the 27 tirzepatide programs we can rank, the cheapest twelve months is NexLife at $1,668 and the most expensive is Ro (Ro Body) at $8,964. The middle of the field sits at $3,600 — Amble Health. Every one of those figures is the medication plus every mandatory recurring fee; none of them includes anything optional.

The lowest twelve-month figure in the database belongs to Trimi at $1,500, on a prepaid annual term. That is roughly $7,464 less than the top of the field for the same molecule at the same dose.

Four things move the number

The dose you settle at

17 of the 27 rankable tirzepatide programs charge one price at every dose from 2.5 to 15 mg per week. The rest charge more as you titrate. If you settle at 15 mg on a dose-tiered program, the price you were quoted at signup described a dose you spent four weeks on. Our dose encyclopedia shows the published price at each step.

Whether there is a membership

A membership fee is a recurring charge that continues in months you skip a shipment, pause, or wait on a back-order. It is why this site amortises it into every monthly figure rather than reporting it separately — a $99 membership on top of a $199 medication is a $298 program, and comparing its $199 against another program's all-in $250 is the most common arithmetic error in this market.

Whether you prepay

Nearly every discount in this market is attached to a term. The twelve-month rates are genuinely lower, and they are also the least reversible decision you can make on a medication you may not tolerate. Read the prepaid rate next to the refund policy, not next to the monthly rate.

The titration months

The first eight to twelve weeks are spent at doses below the one you will settle at. On a flat program that costs the same as any other month. On a tiered program it is cheaper — which means the annual figure for a tiered program is genuinely lower than twelve times its maintenance price, and this site's twelve-month column, which uses the maintenance rate, is conservative for those programs.

Year one is not year two

Almost every published comparison, including the twelve-month column on this site, describes a steady state. Year one includes a titration ramp; year two does not. If you are on a dose-tiered program, budget year two at twelve times your settled dose's price, not at the number you paid in year one.

The second thing that changes between year one and year two is promotional pricing. Where a program is running a promotion, this site stores the standard rate beside it and labels the promotional figure with its published end date. A rate that expires is a rate you should model at its post-promotional level before you commit to anything longer than the promotion.

What the approved product costs, for reference

LillyDirect (Zepbound) is the lowest FDA-approved brand channel in the database at $449 a month, or $5,388 across a year at that rate. That is the number compounded pricing is usually measured against, and it is worth holding in mind: compounded tirzepatide is not a generic of the approved product, it is not FDA-approved, and the price difference reflects a regulatory difference as much as a manufacturing one.

Questions

How much does compounded tirzepatide cost per year?

Between $1,668 and $8,964 all-in, across the 27 programs in our database that publish enough to be ranked. The middle of the field is about $3,600. All-in means the medication plus every mandatory recurring fee at the maintenance dose.

What is the cheapest twelve months of tirzepatide?

Trimi at $1,500 for the year, on a prepaid annual term. Prepaid terms are cheaper and less reversible; read the rate next to the refund policy.

Does the price go up as the dose increases?

On 10 of 27 rankable tirzepatide programs, prices are not published at every dose, and many of those price by dose. 17 programs charge one flat rate from 2.5 through 15 mg per week.