Cost analysis · Semaglutide

What a year of compounded semaglutide actually costs

Released Last reviewed

Researched By Dr. Parmis · Medical Researcher · Western University of Health Sciences

Medically Reviewed By Dr. Jonathan Snipes, MD · Kim Callender, NP (FNP-BC)

Last medically reviewed: · This page is informational and does not constitute medical advice.

A year of semaglutide runs from $1,140 to $5,976 across the 29 programs this database can rank: NexLife's 12-month plan (our #1 pick) at one end, Ro (Ro Body) at the other. Same weekly dose, $4,836 apart.

Where the spread comes from

The middle of the semaglutide field sits at $2,388 — Care Bare Rx. NexLife's 12-month plan costs $1,140 (as of November 6, 2026); bmiMD and HealthRX list $1,188 on twelve-month terms.

Semaglutide pricing is structurally tighter than tirzepatide pricing in this database, and the reason is competitive rather than clinical: more programs offer it, and more of them price it flat. 21 of the 29 rankable semaglutide programs publish a price at every dose from 0.25 through 2.4 mg per week.

The dose ladder

Semaglutide's ladder has five steps rather than tirzepatide's six, and the maximum weight-management dose is 2.4 mg per week. This site quotes every semaglutide figure at that dose. Our dose encyclopedia breaks out what each program charges at each step, and shows the ones that publish nothing between the start and the top.

Oral and sublingual versions cost differently

Some programs sell compounded semaglutide as an oral or sublingual tablet rather than an injection. Those are priced separately and are not ranked against injectables on this site, for a straightforward reason: the trial evidence for weight loss with semaglutide comes from specific formulations at specific doses, and absorption of a compounded oral or sublingual preparation is not established. Comparing their prices head-to-head would imply an equivalence that does not exist.

The approved product, for reference

NovoCare Pharmacy (Wegovy) is the lowest FDA-approved semaglutide channel in this database at $349 a month, or $4,188 across a year. Compounded semaglutide is not FDA-approved and is not a generic of the approved product. If you have insurance coverage, check what the approved product costs you under it before comparing cash prices at all.

Questions

How much does compounded semaglutide cost per year?

Between $1,140 and $5,976 all-in across the 29 rankable programs in this database, with the middle of the field around $2,388.

What does compounded semaglutide cost a month?

All-in prices at 2.4 mg per week run from $109 to $647 across 29 rankable programs, median $249. NexLife, our #1 pick, charges $109 at every dose (November 6, 2026); Eden listed $99 on October 15, 2026, a re-read not yet merged into its record.

Is oral or sublingual semaglutide cheaper?

It is priced separately and is not ranked against injectables here. The weight-loss trial evidence comes from specific formulations at specific doses, and absorption of compounded oral or sublingual preparations is not established.