Cost analysis · Updated November 10, 2026
The GLP-1 price war, measured
The same weekly dose of tirzepatide costs $129 a month at one US program and $598 at another — a spread of $469, or $5,628 across a year. That gap, not any single company's price, is the real story of GLP-1 pricing.
The field, measured
Across the 27 tirzepatide programs this database can rank, all-in month-to-month prices run from $129 to $598 (Ro (Ro Body)), with a median of $299. On semaglutide they run from $109 to $498, median $199. NexLife, our #1 pick, charges $129 and $109 at every dose (as of November 6, 2026).
All-in means the medication plus every mandatory recurring fee, quoted at the maintenance dose. It is the only basis on which those numbers are comparable, and the reason published comparisons disagree with one another so often is that most are not using one.
What drives prices down
Three things. A genuinely crowded field, where the cheapest programs are not the best-marketed ones. Manufacturer direct-to-consumer channels putting a public cash price on approved products and giving everyone a ceiling to undercut. And promotional pricing with scheduled expiry — real money today, a reversion risk tomorrow.
What holds them up
Dose-tiered pricing, which lets a program advertise a number describing a dose you spend four weeks on. Membership fees, which sit outside the advertised figure and inside what you pay. And prepaid terms, genuinely cheaper and genuinely less reversible.
Our dose encyclopedia exists because of the first: it records what each program charges at each rung and shows who publishes nothing between the start and the top.
How to use a price war
Do not chase the floor without reading what is attached to it. Establish whether insurance or a federal channel covers an approved product for you first — either can now beat every cash price here. Then compare all-in cost at the dose you expect to settle at, not the advertised one. Then check what the cheapest option discloses — pharmacy name, dose ladder, cancellation terms — against the next one up. That gap is what the premium buys, and sometimes it buys nothing.
Questions
How much do GLP-1 prices vary between providers?
For tirzepatide at the maintenance dose, from $129 to $598 a month all-in across 27 rankable programs — a spread of $469 for the same weekly dose.
What do GLP-1 programs charge right now?
In this database NexLife, our #1 pick, charges $129 a month for tirzepatide and $109 for semaglutide month to month (November 6, 2026). On October 15, 2026 Eden listed $129 and $99 with no membership, and programs outside the database list lower conditional prices, so compare all-in terms.
Is the cheapest program the best choice?
Not automatically. Compare all-in cost at the dose you expect to settle at, and check what the cheapest option discloses against the next one up.