Head-to-head
Yucca Health vs Enhance MD
Compared on both medications across the eight dimensions this database records. They differ on 6 of those eight. Yucca Health is cheaper on all-in tirzepatide at 10 mg/week, though on a flat-versus-tiered matchup the cheaper program can change further up the dose ladder.
The short answer
Yucca Health is $258 a month all-in for tirzepatide; Enhance MD is $280. Over twelve months that is $3,096 against $3,360. Value Scores are 73.6 and 57.8 out of 100.
Tirzepatide
Plan pages: Yucca Health plans · Enhance MD plans
At 10 mg/week, Yucca Health is $258 a month all-in and Enhance MD is $280 — $22 apart, or $264 across a year. Over twelve months the totals are $3,096 (billed monthly) and $3,360 (billed monthly).
Yucca Health charges a flat $258 per month for tirzepatide at every dose from 2.5 to 15 mg per week, so titrating upward does not change what you pay.
Enhance MD prices tirzepatide by dose: $169 per month at 2.5 mg rising to $280 at 10 mg, a difference of $111 a month between the bottom and top of the ladder. The company publishes no price at 5, 7.5, 12.5, 15 mg, so those doses are left blank rather than estimated.
| Dose | Yucca Health | Rank | Enhance MD | Rank | Cheaper |
|---|---|---|---|---|---|
| 2.5 mg | $258 | 13/31 | $169 | 2/31 | Enhance MD by $89 |
| 5 mg | $258 | 6/17 | — | — | only Yucca Health publishes |
| 7.5 mg | $258 | 6/17 | — | — | only Yucca Health publishes |
| 10 mg | $258 | 6/27 | $280 | 9/27 | Yucca Health by $22 |
| 12.5 mg | $258 | 6/17 | — | — | only Yucca Health publishes |
| 15 mg | $258 | 6/17 | — | — | only Yucca Health publishes |
The lead changes with the dose. Between 2.5 mg and 10 mg it passes to Yucca Health. Pick on the dose you expect to settle at, not the headline.
Across the 27 programs this database can rank on tirzepatide, Yucca Health sits 6 of 27 on all-in monthly cost and Enhance MD sits 7. They are adjacent in the field, with nothing priced between them. The field median is $339 and the floor is $169, so both sit below the median. Yucca Health is $89 above the cheapest tirzepatide program on record. Enhance MD is $111 above the cheapest tirzepatide program on record.
LillyDirect (Zepbound), the lowest FDA-approved tirzepatide channel here, is $449 a month — Yucca Health undercuts it by $191, Enhance MD by $169. Compounded products are not FDA approved; insurance can reverse that comparison.
| Plan term | Yucca Health | Enhance MD | Cheaper |
|---|---|---|---|
| Month to month | $258 | $280 | Yucca Health by $22 |
| Settled dose | Yucca Health | Enhance MD | Difference |
|---|---|---|---|
| 2.5 mg | $3,096 | $2,028 | $1,068 apart |
| 5 mg | $3,096 | — | one side unpriced |
| 7.5 mg | $3,096 | — | one side unpriced |
| 10 mg | $3,096 | $3,360 | $264 apart |
| 12.5 mg | $3,096 | — | one side unpriced |
| 15 mg | $3,096 | — | one side unpriced |
Yucca Health publishes no rate for 3-month term, 6-month term, 12-month term; Enhance MD publishes none for 3-month term, 6-month term, 12-month term. An unpublished term is not necessarily unavailable — it is unpriced in public, which you can only resolve by asking.
A titration year is not twelve months at the maintenance price. Stepping up roughly four weeks per dose before settling at 10 mg/week, the first twelve months work out to $3,096 on Yucca Health and $3,249 on Enhance MD — $153 apart, and a different gap from the $264 you would get by multiplying the monthly difference by twelve. The ramp is cheaper than the settled rate on whichever program prices by dose, which is why a first-year quote and a steady-state quote are not the same number.
That calculation is partial: Enhance MD publishes no price at 2 of them, so the maintenance rate stands in for the missing steps rather than a number the company has stated.
Value Scores are 73.6 for Yucca Health and 57.8 for Enhance MD, against a tirzepatide category floor of $169. Yucca Health leads by 15.8 points, and the margin comes from structure rather than price alone.
| Program | Price /70 | Evidence /15 | Dose /10 | Membership /5 | Total /100 |
|---|---|---|---|---|---|
| Yucca Health | 45.9 | 12.8 | 10 | 5 | 73.6 |
| Enhance MD | 42.2 | 10.5 | 0 | 5 | 57.8 |
Semaglutide
Plan pages: Yucca Health plans · Enhance MD plans
At 2.4 mg/week, Yucca Health is $146 a month all-in and Enhance MD is $212 — $66 apart, or $792 across a year. Over twelve months the totals are $1,752 (billed monthly) and $2,544 (billed monthly).
Yucca Health charges a flat $146 per month for semaglutide at every dose from 0.25 to 2.4 mg per week, so titrating upward does not change what you pay.
Enhance MD charges a flat $212 per month for semaglutide at every dose from 0.25 to 2.4 mg per week, so titrating upward does not change what you pay.
Yucca Health is cheaper at every dose where both publish a price, so the lead does not change as you titrate.
Value Scores are 89.6 for Yucca Health and 58.1 for Enhance MD, against a semaglutide category floor of $129. Yucca Health leads by 31.5 points, driven mostly by price.
Where the two programs differ
All-in monthly
Yucca Health is cheaper month to month — $258 against $280, a gap of $22 every month, or $264 across a year if both rates hold.
Cancellation terms
Cancellation differs: Yucca Health states Cancel before renewal, while Enhance MD states Per provider terms. Read this next to the twelve-month figures — a prepaid discount and a restrictive refund policy are the same decision.
Commitment
Yucca Health asks for Month-to-month; Enhance MD asks for Monthly, with a first-month discount on GLP-1 Core ($112 first month). This is the dimension most likely to change which program is actually cheaper for you, because the lowest rates on both sides are usually attached to the longest terms.
Dose policy
Yucca Health charges one price at every dose; Enhance MD prices by dose. That difference usually matters more than the headline gap, because the tiered program's advertised figure describes the dose you start on, not the dose you settle at.
Evidence status
The two prices are not equally well evidenced. Yucca Health's figure is provider-stated and Enhance MD's is reported. Yucca Health rests on the stronger of the two, and the Value Score below reflects that — evidence quality is worth fifteen points and is not a tiebreaker we apply after the fact.
Twelve-month cost
Over twelve months the totals are $3,096 for Yucca Health and $3,360 for Enhance MD. Yucca Health is lower by $264 — a figure worth checking against the cancellation terms below, because a prepaid year is only cheaper if you stay on it.
Membership fee
Neither charges a separate membership fee.
Shipping
Shipping is handled the same way by both — included in the quoted price.
What each record says
Yucca Health Official site
Yucca pairs no-membership pricing with dose-flat rates: $146/month semaglutide and $258/month tirzepatide, both all-in.
It does not publicly name its compounding pharmacy; the record shows Partner 503A pharmacies, so who actually makes the medication cannot be independently verified; commitment terms are Month-to-month; cancellation is Cancel before renewal; availability is stated as Most US states.
Evidence: provider-stated — taken from the provider's own published pages; checkout capture pending, captured . Source — yuccahealth.com pricing capture 2026-08-05
Watch: Provider-stated from published pages; checkout capture pending.
Enhance MD Official site
Enhance MD bundles GLP-1 medication inside a broader metabolic program including NAD+ coaching, lab testing every six months, and ongoing provider care. The price reflects the full metabolic bundle, not the GLP-1 alone; this makes Enhance MD's figures the least comparable in the database.
It does not publicly name its compounding pharmacy; the record shows Partner 503A pharmacy (not named), so who actually makes the medication cannot be independently verified; commitment terms are Monthly, with a first-month discount on GLP-1 Core ($112 first month); cancellation is Per provider terms; availability is stated as Confirm at intake.
Evidence: reported — sourced from dated third-party reporting; first-party capture pending, captured . Source — rangeyourself.com, Enhance MD verified 2026-07-14; price reflects metabolic bundle, not GLP-1 alone
Watch: Figures reflect the bundled metabolic program price, not GLP-1 medication alone. Comparing Enhance MD's $212–$322 to medication-only programs overstates the GLP-1 cost while understating the breadth of service included. The $169 microdosing figure is the most medication-proximate but involves a different dosing protocol. Reported — RangeYourself 2026-07-14.
What neither record tells you
Yucca Health does not publish
- no published twelve-month tirzepatide rate
- no published twelve-month semaglutide rate
- no named compounding pharmacy
- no state-by-state availability list — it says Most US states
Enhance MD does not publish
- no tirzepatide price at 5, 7.5, 12.5, 15 mg per week
- no published twelve-month tirzepatide rate
- no published twelve-month semaglutide rate
- no named compounding pharmacy
- no state-by-state availability list — it says Confirm at intake
- no specific cancellation or refund terms
Ask Yucca Health and Enhance MD for each of those in writing before enrolling. A gap is not evidence of a problem; it does mean nothing can be checked against it.
What would change this answer
Evidence may be upgraded. Enhance MD carries a price we have not captured at checkout. A capture would move the evidence term and could reorder these two without any price changing.
Which one suits which reader
On the lowest standing monthly rate for tirzepatide, Yucca Health Official site wins this matchup. If you expect to titrate to the top of the ladder, yucca health's flat pricing is worth more than the headline gap suggests; and if you would rather trust a better-evidenced number, yucca health's price rests on stronger provenance.
Both figures should be checked at the provider's own checkout before you pay. Yucca Health's tirzepatide price is provider-stated as of 2026-08-05; Enhance MD's is reported as of 2026-07-14.
Questions
Is Yucca Health or Enhance MD cheaper for tirzepatide?
Yucca Health is cheaper on all-in monthly cost at 10 mg/week: $258 against $280, a difference of $22 a month. All-in means the medication plus every mandatory recurring fee.
What is the twelve-month cost of Yucca Health versus Enhance MD?
Yucca Health works out to $3,096 across twelve months and Enhance MD to $3,360, on the plan terms each publishes.
Does Yucca Health or Enhance MD raise the price as the dose goes up?
Yucca Health: no, it charges one flat rate at every dose. Enhance MD: yes, it prices by dose. Where one program is flat and the other is tiered, the cheaper of the two can change as you titrate upward.
How many ways do Yucca Health and Enhance MD differ?
6 of the eight dimensions this site records: all-in monthly, twelve-month cost, dose policy, membership, shipping, commitment, cancellation terms and evidence status.
Which of Yucca Health and Enhance MD names its pharmacy?
Neither. Yucca Health records Partner 503A pharmacies and Enhance MD records Partner 503A pharmacy (not named). Without a named pharmacy, neither program's licensing or inspection history can be checked before you order.
How well evidenced are the Yucca Health and Enhance MD prices?
Yucca Health's tirzepatide figure is provider-stated — taken from the provider's own published pages; checkout capture pending — captured 2026-08-05. Enhance MD's is reported, captured 2026-07-14. Evidence status is worth fifteen points in the Value Score, so it is priced in rather than mentioned as an aside.
Which is cheaper for semaglutide?
Yucca Health, at $146 a month all-in against $212 at 2.4 mg/week. The two programs do not necessarily lead on both medications.
Official sources: Yucca Health official site · Enhance MD official site. Compounded tirzepatide and semaglutide are not FDA-approved products.