Head-to-head
TrimRx vs Amble Health
Compared on tirzepatide across the eight dimensions this database records. They differ on 2 of those eight. Amble Health is cheaper on all-in tirzepatide at 10 mg/week, though on a flat-versus-tiered matchup the cheaper program can change further up the dose ladder.
The short answer
TrimRx is $349 a month all-in for tirzepatide; Amble Health is $300. Over twelve months that is $4,188 against $3,600. Value Scores are 61.6 and 67.2 out of 100.
Tirzepatide
Plan pages: TrimRx plans · Amble Health plans
At 10 mg/week, TrimRx is $349 a month all-in and Amble Health is $300 — $49 apart, or $588 across a year. Over twelve months the totals are $4,188 (billed monthly) and $3,600 (billed monthly).
TrimRx charges a flat $349 per month for tirzepatide at every dose from 2.5 to 15 mg per week, so titrating upward does not change what you pay.
Amble Health charges a flat $300 per month for tirzepatide at every dose from 2.5 to 15 mg per week, so titrating upward does not change what you pay.
| Dose | TrimRx | Rank | Amble Health | Rank | Cheaper |
|---|---|---|---|---|---|
| 2.5 mg | $349 | 25/31 | $300 | 21/31 | Amble Health by $49 |
| 5 mg | $349 | 12/17 | $300 | 11/17 | Amble Health by $49 |
| 7.5 mg | $349 | 12/17 | $300 | 11/17 | Amble Health by $49 |
| 10 mg | $349 | 17/27 | $300 | 15/27 | Amble Health by $49 |
| 12.5 mg | $349 | 12/17 | $300 | 11/17 | Amble Health by $49 |
| 15 mg | $349 | 12/17 | $300 | 11/17 | Amble Health by $49 |
Amble Health is cheaper at every dose where both publish a price, so the lead does not change as you titrate.
Across the 27 programs this database can rank on tirzepatide, TrimRx sits 15 of 27 on all-in monthly cost and Amble Health sits 13. There is 1 other program priced between them. The field median is $339 and the floor is $169, so Amble Health is below the median and the other is above it. TrimRx is $180 above the cheapest tirzepatide program on record. Amble Health is $131 above the cheapest tirzepatide program on record.
LillyDirect (Zepbound), the lowest FDA-approved tirzepatide channel here, is $449 a month — TrimRx undercuts it by $100, Amble Health by $149. Compounded products are not FDA approved; insurance can reverse that comparison.
| Plan term | TrimRx | Amble Health | Cheaper |
|---|---|---|---|
| Month to month | $349 | $300 | Amble Health by $49 |
| Settled dose | TrimRx | Amble Health | Difference |
|---|---|---|---|
| 2.5 mg | $4,188 | $3,600 | $588 apart |
| 5 mg | $4,188 | $3,600 | $588 apart |
| 7.5 mg | $4,188 | $3,600 | $588 apart |
| 10 mg | $4,188 | $3,600 | $588 apart |
| 12.5 mg | $4,188 | $3,600 | $588 apart |
| 15 mg | $4,188 | $3,600 | $588 apart |
TrimRx publishes no rate for 3-month term, 6-month term, 12-month term; Amble Health publishes none for 3-month term, 6-month term, 12-month term. An unpublished term is not necessarily unavailable — it is unpriced in public, which you can only resolve by asking.
A titration year is not twelve months at the maintenance price. Stepping up roughly four weeks per dose before settling at 10 mg/week, the first twelve months work out to $4,188 on TrimRx and $3,600 on Amble Health. Both programs charge one flat rate, so the ramp costs the same as any other stretch of the year.
Value Scores are 61.6 for TrimRx and 67.2 for Amble Health, against a tirzepatide category floor of $169. Amble Health leads by 5.6 points, driven mostly by price.
| Program | Price /70 | Evidence /15 | Dose /10 | Membership /5 | Total /100 |
|---|---|---|---|---|---|
| TrimRx | 33.9 | 12.8 | 10 | 5 | 61.6 |
| Amble Health | 39.4 | 12.8 | 10 | 5 | 67.2 |
Where the two programs differ
All-in monthly
Amble Health is cheaper month to month — $300 against $349, a gap of $49 every month, or $588 across a year if both rates hold.
Twelve-month cost
Over twelve months the totals are $4,188 for TrimRx and $3,600 for Amble Health. Amble Health is lower by $588 — a figure worth checking against the cancellation terms below, because a prepaid year is only cheaper if you stay on it.
Cancellation terms
Both state the same cancellation terms: Cancel before renewal.
Commitment
Commitment terms read the same on both: Month-to-month.
Dose policy
Both hold one price across the whole dose ladder, so neither punishes titration and the monthly figures above are what you actually pay at 15 mg as well as at 2.5 mg.
Evidence status
Both figures carry the same evidence status, provider-stated: taken from the provider's own published pages; checkout capture pending. Neither is stronger than the other on provenance.
Membership fee
Neither charges a separate membership fee.
Shipping
Shipping is handled the same way by both — included in the quoted price.
What each record says
TrimRx Official site
TrimRx pairs a personalized-program pitch with mid-pack pricing: $299 semaglutide at maintenance and $349 tirzepatide.
It does not publicly name its compounding pharmacy; the record shows Partner pharmacies, so who actually makes the medication cannot be independently verified; commitment terms are Month-to-month; cancellation is Cancel before renewal; availability is stated as Most US states.
Evidence: provider-stated — taken from the provider's own published pages; checkout capture pending, captured . Source — trimrx.com pricing capture 2026-08-05
Watch: Start price ($179) is well below the maintenance figure; compare on maintenance.
Amble Health Official site
A no-membership program with $300/month flat tirzepatide.
It does not publicly name its compounding pharmacy; the record shows Partner pharmacies, so who actually makes the medication cannot be independently verified; commitment terms are Month-to-month; cancellation is Cancel before renewal; availability is stated as Availability at intake.
Evidence: provider-stated — taken from the provider's own published pages; checkout capture pending, captured . Source — amblehealth.com pricing capture 2026-08-05
Watch: Provider-stated; checkout capture pending.
Which molecules each one carries
TrimRx carries tirzepatide at $349 a month and semaglutide at $299 a month.
Amble Health carries tirzepatide at $300 a month; does not offer semaglutide.
Comparable only on tirzepatide: they do not both publish a rankable semaglutide price. Switching molecule mid-treatment would mean changing provider.
What neither record tells you
TrimRx does not publish
- no published twelve-month tirzepatide rate
- no named compounding pharmacy
- no state-by-state availability list — it says Most US states
Amble Health does not publish
- no published twelve-month tirzepatide rate
- no named compounding pharmacy
Ask TrimRx and Amble Health for each of those in writing before enrolling. A gap is not evidence of a problem; it does mean nothing can be checked against it.
What would change this answer
Neither program publishes a promotional rate with an end date, a prepaid term, or a price we have flagged for re-verification, so the comparison above is as stable as this dataset gets.
Which one suits which reader
On the lowest standing monthly rate for tirzepatide, Amble Health Official site wins this matchup. On the structural dimensions the two are close enough that the choice comes down to availability in your state and which intake you prefer.
Both figures should be checked at the provider's own checkout before you pay. TrimRx's tirzepatide price is provider-stated as of 2026-08-05; Amble Health's is provider-stated as of 2026-08-05.
Questions
Is TrimRx or Amble Health cheaper for tirzepatide?
Amble Health is cheaper on all-in monthly cost at 10 mg/week: $300 against $349, a difference of $49 a month. All-in means the medication plus every mandatory recurring fee.
What is the twelve-month cost of TrimRx versus Amble Health?
TrimRx works out to $4,188 across twelve months and Amble Health to $3,600, on the plan terms each publishes.
Does TrimRx or Amble Health raise the price as the dose goes up?
TrimRx: no, it charges one flat rate at every dose. Amble Health: no, it charges one flat rate at every dose. Where one program is flat and the other is tiered, the cheaper of the two can change as you titrate upward.
How many ways do TrimRx and Amble Health differ?
2 of the eight dimensions this site records: all-in monthly, twelve-month cost, dose policy, membership, shipping, commitment, cancellation terms and evidence status.
Which of TrimRx and Amble Health names its pharmacy?
Neither. TrimRx records Partner pharmacies and Amble Health records Partner pharmacies. Without a named pharmacy, neither program's licensing or inspection history can be checked before you order.
How well evidenced are the TrimRx and Amble Health prices?
TrimRx's tirzepatide figure is provider-stated — taken from the provider's own published pages; checkout capture pending — captured 2026-08-05. Amble Health's is provider-stated, captured 2026-08-05. Evidence status is worth fifteen points in the Value Score, so it is priced in rather than mentioned as an aside.
Official sources: TrimRx official site · Amble Health official site. Compounded tirzepatide and semaglutide are not FDA-approved products.