Head-to-head
SkinnyRx vs LifeMD
Compared on both medications across the eight dimensions this database records. They differ on 4 of those eight. SkinnyRx is cheaper on all-in tirzepatide at 10 mg/week, though on a flat-versus-tiered matchup the cheaper program can change further up the dose ladder.
The short answer
SkinnyRx is $299 a month all-in for tirzepatide; LifeMD is $746. Over twelve months that is $3,588 against $8,952. Value Scores are 67.3 and 38.6 out of 100.
Tirzepatide
Plan pages: SkinnyRx plans · LifeMD plans
At 10 mg/week, SkinnyRx is $299 a month all-in and LifeMD is $746 — $447 apart, or $5,364 across a year. Over twelve months the totals are $3,588 (billed monthly) and $8,952 (billed monthly).
SkinnyRx charges a flat $299 per month for tirzepatide at every dose from 2.5 to 15 mg per week, so titrating upward does not change what you pay.
LifeMD charges a flat $597 per month for tirzepatide at every dose from 2.5 to 15 mg per week, so titrating upward does not change what you pay.
| Dose | SkinnyRx | Rank | LifeMD | Rank | Cheaper |
|---|---|---|---|---|---|
| 2.5 mg | $299 | 20/31 | $597 | 31/31 | SkinnyRx by $298 |
| 5 mg | $299 | 10/17 | $597 | 17/17 | SkinnyRx by $298 |
| 7.5 mg | $299 | 10/17 | $597 | 17/17 | SkinnyRx by $298 |
| 10 mg | $299 | 14/27 | $597 | 26/27 | SkinnyRx by $298 |
| 12.5 mg | $299 | 10/17 | $597 | 17/17 | SkinnyRx by $298 |
| 15 mg | $299 | 10/17 | $597 | 17/17 | SkinnyRx by $298 |
SkinnyRx is cheaper at every dose where both publish a price, so the lead does not change as you titrate.
Across the 27 programs this database can rank on tirzepatide, SkinnyRx sits 12 of 27 on all-in monthly cost and LifeMD sits 26. There are 13 other programs priced between them. The field median is $339 and the floor is $169, so SkinnyRx is below the median and the other is above it. SkinnyRx is $130 above the cheapest tirzepatide program on record. LifeMD is $577 above the cheapest tirzepatide program on record.
LillyDirect (Zepbound), the lowest FDA-approved tirzepatide channel here, is $449 a month — SkinnyRx undercuts it by $150, LifeMD by $-297. Compounded products are not FDA approved; insurance can reverse that comparison.
| Plan term | SkinnyRx | LifeMD | Cheaper |
|---|---|---|---|
| Month to month | $299 | $597 | SkinnyRx by $298 |
| Settled dose | SkinnyRx | LifeMD | Difference |
|---|---|---|---|
| 2.5 mg | $3,588 | $8,952 | $5,364 apart |
| 5 mg | $3,588 | $8,952 | $5,364 apart |
| 7.5 mg | $3,588 | $8,952 | $5,364 apart |
| 10 mg | $3,588 | $8,952 | $5,364 apart |
| 12.5 mg | $3,588 | $8,952 | $5,364 apart |
| 15 mg | $3,588 | $8,952 | $5,364 apart |
SkinnyRx publishes no rate for 3-month term, 6-month term, 12-month term; LifeMD publishes none for 3-month term, 6-month term, 12-month term. An unpublished term is not necessarily unavailable — it is unpriced in public, which you can only resolve by asking.
A titration year is not twelve months at the maintenance price. Stepping up roughly four weeks per dose before settling at 10 mg/week, the first twelve months work out to $3,588 on SkinnyRx and $8,952 on LifeMD. Both programs charge one flat rate, so the ramp costs the same as any other stretch of the year.
Value Scores are 67.3 for SkinnyRx and 38.6 for LifeMD, against a tirzepatide category floor of $169. SkinnyRx leads by 28.7 points, driven mostly by price.
| Program | Price /70 | Evidence /15 | Dose /10 | Membership /5 | Total /100 |
|---|---|---|---|---|---|
| SkinnyRx | 39.6 | 12.8 | 10 | 5 | 67.3 |
| LifeMD | 15.9 | 12.8 | 10 | 0 | 38.6 |
Semaglutide
Plan pages: SkinnyRx plans · LifeMD plans
At 2.4 mg/week, SkinnyRx is $199 a month all-in and LifeMD is $497 — $298 apart, or $3,576 across a year. Over twelve months the totals are $2,388 (billed monthly) and $5,964 (billed monthly).
SkinnyRx charges a flat $199 per month for semaglutide at every dose from 0.25 to 2.4 mg per week, so titrating upward does not change what you pay.
LifeMD charges a flat $348 per month for semaglutide at every dose from 0.25 to 2.4 mg per week, so titrating upward does not change what you pay.
SkinnyRx is cheaper at every dose where both publish a price, so the lead does not change as you titrate.
Value Scores are 73.1 for SkinnyRx and 40.9 for LifeMD, against a semaglutide category floor of $129. SkinnyRx leads by 32.2 points, driven mostly by price.
Where the two programs differ
All-in monthly
SkinnyRx is cheaper month to month — $299 against $746, a gap of $447 every month, or $5,364 across a year if both rates hold.
Cancellation terms
Cancellation differs: SkinnyRx states Cancel before renewal, while LifeMD states Cancel anytime. Read this next to the twelve-month figures — a prepaid discount and a restrictive refund policy are the same decision.
Membership fee
LifeMD charges a membership of $149 a month on top of the medication. That is already folded into the all-in figures above — it is broken out here because a membership is a recurring charge that continues even in a month you skip a shipment.
Twelve-month cost
Over twelve months the totals are $3,588 for SkinnyRx and $8,952 for LifeMD. SkinnyRx is lower by $5,364 — a figure worth checking against the cancellation terms below, because a prepaid year is only cheaper if you stay on it.
Commitment
Commitment terms read the same on both: Month-to-month.
Dose policy
Both hold one price across the whole dose ladder, so neither punishes titration and the monthly figures above are what you actually pay at 15 mg as well as at 2.5 mg.
Evidence status
Both figures carry the same evidence status, provider-stated: taken from the provider's own published pages; checkout capture pending. Neither is stronger than the other on provenance.
Shipping
Shipping is handled the same way by both — included in the quoted price.
What each record says
SkinnyRx Official site
A straightforward no-membership program: $199/month semaglutide, $299/month tirzepatide, flat at every dose.
It does not publicly name its compounding pharmacy; the record shows Partner pharmacies, so who actually makes the medication cannot be independently verified; commitment terms are Month-to-month; cancellation is Cancel before renewal; availability is stated as Most US states.
Evidence: provider-stated — taken from the provider's own published pages; checkout capture pending, captured . Source — skinnyrx.com pricing capture 2026-08-05
Watch: Provider-stated; checkout capture pending.
LifeMD Official site
LifeMD attaches a $149/month program fee to medication pricing; its compounded tirzepatide all-in figure ($597) is the highest in our index, though its insurance-navigation pathway for brand products is a genuine strength.
It does not publicly name its compounding pharmacy; the record shows Partner pharmacies, so who actually makes the medication cannot be independently verified; commitment terms are Month-to-month; cancellation is Cancel anytime; availability is stated as 50 states.
Evidence: provider-stated — taken from the provider's own published pages; checkout capture pending, captured . Source — lifemd.com pricing capture 2026-08-05
Watch: Highest all-in compounded tirzepatide in the index; the value case rests on clinical service and insurance help, not price.
What neither record tells you
SkinnyRx does not publish
- no published twelve-month tirzepatide rate
- no published twelve-month semaglutide rate
- no named compounding pharmacy
- no state-by-state availability list — it says Most US states
LifeMD does not publish
- no published twelve-month tirzepatide rate
- no published twelve-month semaglutide rate
- no named compounding pharmacy
Ask SkinnyRx and LifeMD for each of those in writing before enrolling. A gap is not evidence of a problem; it does mean nothing can be checked against it.
What would change this answer
Neither program publishes a promotional rate with an end date, a prepaid term, or a price we have flagged for re-verification, so the comparison above is as stable as this dataset gets.
Which one suits which reader
On the lowest standing monthly rate for tirzepatide, SkinnyRx Official site wins this matchup. If you want to be able to pause without still paying, skinnyrx carries no membership.
Both figures should be checked at the provider's own checkout before you pay. SkinnyRx's tirzepatide price is provider-stated as of 2026-08-05; LifeMD's is provider-stated as of 2026-08-05.
Questions
Is SkinnyRx or LifeMD cheaper for tirzepatide?
SkinnyRx is cheaper on all-in monthly cost at 10 mg/week: $299 against $746, a difference of $447 a month. All-in means the medication plus every mandatory recurring fee.
What is the twelve-month cost of SkinnyRx versus LifeMD?
SkinnyRx works out to $3,588 across twelve months and LifeMD to $8,952, on the plan terms each publishes.
Does SkinnyRx or LifeMD raise the price as the dose goes up?
SkinnyRx: no, it charges one flat rate at every dose. LifeMD: no, it charges one flat rate at every dose. Where one program is flat and the other is tiered, the cheaper of the two can change as you titrate upward.
How many ways do SkinnyRx and LifeMD differ?
4 of the eight dimensions this site records: all-in monthly, twelve-month cost, dose policy, membership, shipping, commitment, cancellation terms and evidence status.
Which of SkinnyRx and LifeMD names its pharmacy?
Neither. SkinnyRx records Partner pharmacies and LifeMD records Partner pharmacies. Without a named pharmacy, neither program's licensing or inspection history can be checked before you order.
How well evidenced are the SkinnyRx and LifeMD prices?
SkinnyRx's tirzepatide figure is provider-stated — taken from the provider's own published pages; checkout capture pending — captured 2026-08-05. LifeMD's is provider-stated, captured 2026-08-05. Evidence status is worth fifteen points in the Value Score, so it is priced in rather than mentioned as an aside.
Which is cheaper for semaglutide?
SkinnyRx, at $199 a month all-in against $497 at 2.4 mg/week. The two programs do not necessarily lead on both medications.
Official sources: SkinnyRx official site · LifeMD official site. Compounded tirzepatide and semaglutide are not FDA-approved products.