Head-to-head
LillyDirect (Zepbound) vs Eden
Compared on tirzepatide across the eight dimensions this database records. They differ on 6 of those eight. LillyDirect (Zepbound) is cheaper on all-in tirzepatide at 10 mg/week, though on a flat-versus-tiered matchup the cheaper program can change further up the dose ladder.
The short answer
LillyDirect (Zepbound) is $449 a month all-in for tirzepatide; Eden is $507. Over twelve months that is $5,388 against $6,084. Value Scores are 46.3 and 36.1 out of 100.
Tirzepatide
Plan pages: LillyDirect (Zepbound) plans · Eden plans
At 10 mg/week, LillyDirect (Zepbound) is $449 a month all-in and Eden is $507 — $58 apart, or $696 across a year. Over twelve months the totals are $5,388 (billed monthly) and $6,084 (billed monthly).
LillyDirect (Zepbound) prices tirzepatide by dose: $299 per month at 2.5 mg rising to $449 at 7.5 mg, a difference of $150 a month between the bottom and top of the ladder.
Eden prices tirzepatide by dose: $348 per month at 2.5 mg rising to $408 at 10 mg, a difference of $60 a month between the bottom and top of the ladder. The company publishes no price at 5, 7.5, 12.5, 15 mg, so those doses are left blank rather than estimated.
| Dose | LillyDirect (Zepbound) | Rank | Eden | Rank | Cheaper |
|---|---|---|---|---|---|
| 2.5 mg | $299 | 18/31 | $348 | 23/31 | LillyDirect (Zepbound) by $49 |
| 5 mg | $399 | 14/17 | — | — | only LillyDirect (Zepbound) publishes |
| 7.5 mg | $449 | 16/17 | — | — | only LillyDirect (Zepbound) publishes |
| 10 mg | $449 | 24/27 | $408 | 23/27 | Eden by $41 |
| 12.5 mg | $449 | 16/17 | — | — | only LillyDirect (Zepbound) publishes |
| 15 mg | $449 | 16/17 | — | — | only LillyDirect (Zepbound) publishes |
The lead changes with the dose. Between 2.5 mg and 10 mg it passes to Eden. Pick on the dose you expect to settle at, not the headline.
Across the 27 programs this database can rank on tirzepatide, LillyDirect (Zepbound) sits 23 of 27 on all-in monthly cost and Eden sits 24. They are adjacent in the field, with nothing priced between them. The field median is $339 and the floor is $169, so both sit above the median. LillyDirect (Zepbound) is $280 above the cheapest tirzepatide program on record. Eden is $338 above the cheapest tirzepatide program on record.
LillyDirect (Zepbound), the lowest FDA-approved tirzepatide channel here, is $449 a month — LillyDirect (Zepbound) undercuts it by $0, Eden by $-58. Compounded products are not FDA approved; insurance can reverse that comparison.
| Plan term | LillyDirect (Zepbound) | Eden | Cheaper |
|---|---|---|---|
| Month to month | $449 | $408 | Eden by $41 |
| Settled dose | LillyDirect (Zepbound) | Eden | Difference |
|---|---|---|---|
| 2.5 mg | $3,588 | $5,364 | $1,776 apart |
| 5 mg | $4,788 | — | one side unpriced |
| 7.5 mg | $5,388 | — | one side unpriced |
| 10 mg | $5,388 | $6,084 | $696 apart |
| 12.5 mg | $5,388 | — | one side unpriced |
| 15 mg | $5,388 | — | one side unpriced |
LillyDirect (Zepbound) publishes no rate for 3-month term, 6-month term, 12-month term; Eden publishes none for 3-month term, 6-month term, 12-month term. An unpublished term is not necessarily unavailable — it is unpriced in public, which you can only resolve by asking.
A titration year is not twelve months at the maintenance price. Stepping up roughly four weeks per dose before settling at 10 mg/week, the first twelve months work out to $5,188 on LillyDirect (Zepbound) and $6,024 on Eden — $836 apart, and a different gap from the $696 you would get by multiplying the monthly difference by twelve. The ramp is cheaper than the settled rate on whichever program prices by dose, which is why a first-year quote and a steady-state quote are not the same number.
That calculation is partial: Eden publishes no price at 2 of them, so the maintenance rate stands in for the missing steps rather than a number the company has stated.
Value Scores are 46.3 for LillyDirect (Zepbound) and 36.1 for Eden, against a tirzepatide category floor of $169. LillyDirect (Zepbound) leads by 10.2 points, and the margin comes from structure rather than price alone.
| Program | Price /70 | Evidence /15 | Dose /10 | Membership /5 | Total /100 |
|---|---|---|---|---|---|
| LillyDirect (Zepbound) | 26.4 | 15.0 | 0 | 5 | 46.3 |
| Eden | 23.3 | 12.8 | 0 | 0 | 36.1 |
Where the two programs differ
All-in monthly
LillyDirect (Zepbound) is cheaper month to month — $449 against $507, a gap of $58 every month, or $696 across a year if both rates hold.
Cancellation terms
Cancellation differs: LillyDirect (Zepbound) states No subscription lock, while Eden states Cancel anytime. Read this next to the twelve-month figures — a prepaid discount and a restrictive refund policy are the same decision.
Commitment
LillyDirect (Zepbound) asks for None; Journey Program pricing requires refill within 45 days on 7.5 mg+; Eden asks for Month-to-month. This is the dimension most likely to change which program is actually cheaper for you, because the lowest rates on both sides are usually attached to the longest terms.
Evidence status
The two prices are not equally well evidenced. LillyDirect (Zepbound)'s figure is verified and Eden's is provider-stated. LillyDirect (Zepbound) rests on the stronger of the two, and the Value Score below reflects that — evidence quality is worth fifteen points and is not a tiebreaker we apply after the fact.
Membership fee
Eden charges a membership of $99 a month on top of the medication. That is already folded into the all-in figures above — it is broken out here because a membership is a recurring charge that continues even in a month you skip a shipment.
Twelve-month cost
Over twelve months the totals are $5,388 for LillyDirect (Zepbound) and $6,084 for Eden. LillyDirect (Zepbound) is lower by $696 — a figure worth checking against the cancellation terms below, because a prepaid year is only cheaper if you stay on it.
Dose policy
Both price by dose, so both advertised figures understate the cost of a titration year. Compare the ladders above rather than the headline rates.
Shipping
Shipping is handled the same way by both — included in the quoted price.
What each record says
LillyDirect (Zepbound) Official site
The manufacturer's own cash channel for FDA-approved Zepbound single-dose vials: $299/month at 2.5 mg, $399 at 5 mg, and $449 for every dose from 7.5 to 15 mg through the Self Pay Journey Program — provided each refill lands within 45 days of the last, otherwise that refill reverts to $599–$1,049 by dose. This is the cheapest FDA-approved tirzepatide in the country and the benchmark every compounded price should be judged against.
It names its compounding pharmacy — Eli Lilly self-pay pharmacy (GiftHealth), recorded as Manufacturer direct — which can be checked against state board licensing and FDA inspection records before you order; commitment terms are None; Journey Program pricing requires refill within 45 days on 7.5 mg+; cancellation is No subscription lock; availability is stated as 50 states.
Evidence: verified — captured at checkout by our desk on the stated date, captured . Source — Lilly investor announcement Dec 1, 2025 + LillyDirect program pages; corroborated by drugs.com pricing review updated Jun 12, 2026
Watch: The 45-day refill window is the whole game: one late refill at 10 mg costs $699 instead of $449.
Eden Official site
Eden attaches a $99/month membership to tiered medication pricing; all-in figures land at $198 semaglutide and $408 tirzepatide at maintenance.
It does not publicly name its compounding pharmacy; the record shows Partner pharmacies, so who actually makes the medication cannot be independently verified; commitment terms are Month-to-month; cancellation is Cancel anytime; availability is stated as Most US states.
Evidence: provider-stated — taken from the provider's own published pages; checkout capture pending, captured . Source — tryeden.com pricing capture 2026-08-05
Watch: Membership plus dose tiering makes Eden's advertised numbers diverge sharply from all-in cost.
Which molecules each one carries
LillyDirect (Zepbound) carries tirzepatide at $449 a month; does not offer semaglutide.
Eden carries tirzepatide at $507 a month and semaglutide at $297 a month.
Comparable only on tirzepatide: they do not both publish a rankable semaglutide price. Switching molecule mid-treatment would mean changing provider.
What neither record tells you
LillyDirect (Zepbound) does not publish
- no published twelve-month tirzepatide rate
Eden does not publish
- no tirzepatide price at 5, 7.5, 12.5, 15 mg per week
- no published twelve-month tirzepatide rate
- no named compounding pharmacy
- no state-by-state availability list — it says Most US states
Ask LillyDirect (Zepbound) and Eden for each of those in writing before enrolling. A gap is not evidence of a problem; it does mean nothing can be checked against it.
What would change this answer
Neither program publishes a promotional rate with an end date, a prepaid term, or a price we have flagged for re-verification, so the comparison above is as stable as this dataset gets.
Which one suits which reader
On the lowest standing monthly rate for tirzepatide, LillyDirect (Zepbound) Official site wins this matchup. If you want to be able to pause without still paying, lillydirect (zepbound) carries no membership; and if you would rather trust a better-evidenced number, lillydirect (zepbound)'s price rests on stronger provenance.
Both figures should be checked at the provider's own checkout before you pay. LillyDirect (Zepbound)'s tirzepatide price is verified as of 2026-08-11; Eden's is provider-stated as of 2026-08-05.
Questions
Is LillyDirect (Zepbound) or Eden cheaper for tirzepatide?
LillyDirect (Zepbound) is cheaper on all-in monthly cost at 10 mg/week: $449 against $507, a difference of $58 a month. All-in means the medication plus every mandatory recurring fee.
What is the twelve-month cost of LillyDirect (Zepbound) versus Eden?
LillyDirect (Zepbound) works out to $5,388 across twelve months and Eden to $6,084, on the plan terms each publishes.
Does LillyDirect (Zepbound) or Eden raise the price as the dose goes up?
LillyDirect (Zepbound): yes, it prices by dose. Eden: yes, it prices by dose. Where one program is flat and the other is tiered, the cheaper of the two can change as you titrate upward.
How many ways do LillyDirect (Zepbound) and Eden differ?
6 of the eight dimensions this site records: all-in monthly, twelve-month cost, dose policy, membership, shipping, commitment, cancellation terms and evidence status.
Which of LillyDirect (Zepbound) and Eden names its pharmacy?
LillyDirect (Zepbound) does — Eli Lilly self-pay pharmacy (GiftHealth). Eden does not, recording only Partner pharmacies, so who makes its medication cannot be independently verified.
How well evidenced are the LillyDirect (Zepbound) and Eden prices?
LillyDirect (Zepbound)'s tirzepatide figure is verified — captured at checkout by our desk on the stated date — captured 2026-08-11. Eden's is provider-stated, captured 2026-08-05. Evidence status is worth fifteen points in the Value Score, so it is priced in rather than mentioned as an aside.
Official sources: LillyDirect (Zepbound) official site · Eden official site. Compounded tirzepatide and semaglutide are not FDA-approved products.