Head-to-head
Hims & Hers vs LillyDirect (Zepbound)
Compared on tirzepatide across the eight dimensions this database records. They differ on 7 of those eight. LillyDirect (Zepbound) is cheaper on all-in tirzepatide at 10 mg/week, though on a flat-versus-tiered matchup the cheaper program can change further up the dose ladder.
The short answer
Hims & Hers is $697 a month all-in for tirzepatide; LillyDirect (Zepbound) is $449. Over twelve months that is $8,364 against $5,388. Value Scores are 27.5 and 46.3 out of 100.
Tirzepatide
Plan pages: Hims & Hers plans · LillyDirect (Zepbound) plans
At 10 mg/week, Hims & Hers is $697 a month all-in and LillyDirect (Zepbound) is $449 — $248 apart, or $2,976 across a year. Over twelve months the totals are $8,364 (billed monthly) and $5,388 (billed monthly).
Hims & Hers charges a flat $548 per month for tirzepatide at every dose from 2.5 to 15 mg per week, so titrating upward does not change what you pay. The company publishes no price at 5, 7.5, 12.5, 15 mg, so those doses are left blank rather than estimated.
LillyDirect (Zepbound) prices tirzepatide by dose: $299 per month at 2.5 mg rising to $449 at 7.5 mg, a difference of $150 a month between the bottom and top of the ladder.
| Dose | Hims & Hers | Rank | LillyDirect (Zepbound) | Rank | Cheaper |
|---|---|---|---|---|---|
| 2.5 mg | $548 | 30/31 | $299 | 18/31 | LillyDirect (Zepbound) by $249 |
| 5 mg | — | — | $399 | 14/17 | only LillyDirect (Zepbound) publishes |
| 7.5 mg | — | — | $449 | 16/17 | only LillyDirect (Zepbound) publishes |
| 10 mg | $548 | 25/27 | $449 | 24/27 | LillyDirect (Zepbound) by $99 |
| 12.5 mg | — | — | $449 | 16/17 | only LillyDirect (Zepbound) publishes |
| 15 mg | — | — | $449 | 16/17 | only LillyDirect (Zepbound) publishes |
LillyDirect (Zepbound) is cheaper at every dose where both publish a price, so the lead does not change as you titrate.
Across the 27 programs this database can rank on tirzepatide, Hims & Hers sits 25 of 27 on all-in monthly cost and LillyDirect (Zepbound) sits 23. There is 1 other program priced between them. The field median is $339 and the floor is $169, so both sit above the median. Hims & Hers is $528 above the cheapest tirzepatide program on record. LillyDirect (Zepbound) is $280 above the cheapest tirzepatide program on record.
LillyDirect (Zepbound), the lowest FDA-approved tirzepatide channel here, is $449 a month — Hims & Hers undercuts it by $-248, LillyDirect (Zepbound) by $0. Compounded products are not FDA approved; insurance can reverse that comparison.
| Plan term | Hims & Hers | LillyDirect (Zepbound) | Cheaper |
|---|---|---|---|
| Month to month | $548 | $449 | LillyDirect (Zepbound) by $99 |
| Settled dose | Hims & Hers | LillyDirect (Zepbound) | Difference |
|---|---|---|---|
| 2.5 mg | $8,364 | $3,588 | $4,776 apart |
| 5 mg | — | $4,788 | one side unpriced |
| 7.5 mg | — | $5,388 | one side unpriced |
| 10 mg | $8,364 | $5,388 | $2,976 apart |
| 12.5 mg | — | $5,388 | one side unpriced |
| 15 mg | — | $5,388 | one side unpriced |
Hims & Hers publishes no rate for 3-month term, 6-month term, 12-month term; LillyDirect (Zepbound) publishes none for 3-month term, 6-month term, 12-month term. An unpublished term is not necessarily unavailable — it is unpriced in public, which you can only resolve by asking.
A titration year is not twelve months at the maintenance price. Stepping up roughly four weeks per dose before settling at 10 mg/week, the first twelve months work out to $8,364 on Hims & Hers and $5,188 on LillyDirect (Zepbound) — $3,176 apart, and a different gap from the $2,976 you would get by multiplying the monthly difference by twelve. The ramp is cheaper than the settled rate on whichever program prices by dose, which is why a first-year quote and a steady-state quote are not the same number.
That calculation is partial: Hims & Hers publishes no price at 2 of the 6 doses, so the maintenance rate stands in for the missing steps rather than a number the company has stated.
Value Scores are 27.5 for Hims & Hers and 46.3 for LillyDirect (Zepbound), against a tirzepatide category floor of $169. LillyDirect (Zepbound) leads by 18.8 points, and the margin comes from structure rather than price alone.
| Program | Price /70 | Evidence /15 | Dose /10 | Membership /5 | Total /100 |
|---|---|---|---|---|---|
| Hims & Hers | 17.0 | 10.5 | 0 | 0 | 27.5 |
| LillyDirect (Zepbound) | 26.4 | 15.0 | 0 | 5 | 46.3 |
Where the two programs differ
All-in monthly
LillyDirect (Zepbound) is cheaper month to month — $449 against $697, a gap of $248 every month, or $2,976 across a year if both rates hold.
Cancellation terms
Cancellation differs: Hims & Hers states Cancel anytime, while LillyDirect (Zepbound) states No subscription lock. Read this next to the twelve-month figures — a prepaid discount and a restrictive refund policy are the same decision.
Commitment
Hims & Hers asks for Membership month-to-month ($39 first month); LillyDirect (Zepbound) asks for None; Journey Program pricing requires refill within 45 days on 7.5 mg+. This is the dimension most likely to change which program is actually cheaper for you, because the lowest rates on both sides are usually attached to the longest terms.
Evidence status
The two prices are not equally well evidenced. Hims & Hers's figure is reported and LillyDirect (Zepbound)'s is verified. LillyDirect (Zepbound) rests on the stronger of the two, and the Value Score below reflects that — evidence quality is worth fifteen points and is not a tiebreaker we apply after the fact.
Membership fee
Hims & Hers charges a membership of $149 a month on top of the medication. That is already folded into the all-in figures above — it is broken out here because a membership is a recurring charge that continues even in a month you skip a shipment.
Shipping
Hims & Hers bills shipping separately at $5; the other includes it.
Twelve-month cost
Over twelve months the totals are $8,364 for Hims & Hers and $5,388 for LillyDirect (Zepbound). LillyDirect (Zepbound) is lower by $2,976 — a figure worth checking against the cancellation terms below, because a prepaid year is only cheaper if you stay on it.
Dose policy
Both price by dose, so both advertised figures understate the cost of a titration year. Compare the ladders above rather than the headline rates.
What each record says
Hims & Hers Official site
After settling with Novo Nordisk on March 9, 2026 and exiting compounded semaglutide for new patients, Hims & Hers now runs a branded-only GLP-1 service: Wegovy injection $299/month, oral Wegovy $249/month, and Zepbound $399/month, on top of a $149/month membership ($39 first month) plus $5 shipping.
It names its compounding pharmacy — Brand fulfillment (Wegovy, oral Wegovy, Zepbound) + partner pharmacy, recorded as Brand channel — which can be checked against state board licensing and FDA inspection records before you order; commitment terms are Membership month-to-month ($39 first month); cancellation is Cancel anytime; availability is stated as 50 states.
Evidence: reported — sourced from dated third-party reporting; first-party capture pending, captured . Source — Post-settlement pricing reported May–Jun 2026 (Wegovy $299 / oral $249 / Zepbound $399 + $149 membership + $5 shipping); first-party checkout capture pending
Watch: The membership is the number that moves the math: a $299 Wegovy pen becomes ~$453/month all-in. Compare against going to NovoCare or LillyDirect directly.
LillyDirect (Zepbound) Official site
The manufacturer's own cash channel for FDA-approved Zepbound single-dose vials: $299/month at 2.5 mg, $399 at 5 mg, and $449 for every dose from 7.5 to 15 mg through the Self Pay Journey Program — provided each refill lands within 45 days of the last, otherwise that refill reverts to $599–$1,049 by dose. This is the cheapest FDA-approved tirzepatide in the country and the benchmark every compounded price should be judged against.
It names its compounding pharmacy — Eli Lilly self-pay pharmacy (GiftHealth), recorded as Manufacturer direct — which can be checked against state board licensing and FDA inspection records before you order; commitment terms are None; Journey Program pricing requires refill within 45 days on 7.5 mg+; cancellation is No subscription lock; availability is stated as 50 states.
Evidence: verified — captured at checkout by our desk on the stated date, captured . Source — Lilly investor announcement Dec 1, 2025 + LillyDirect program pages; corroborated by drugs.com pricing review updated Jun 12, 2026
Watch: The 45-day refill window is the whole game: one late refill at 10 mg costs $699 instead of $449.
Which molecules each one carries
Hims & Hers carries tirzepatide at $697 a month and semaglutide at $602 a month.
LillyDirect (Zepbound) carries tirzepatide at $449 a month; does not offer semaglutide.
Comparable only on tirzepatide: they do not both publish a rankable semaglutide price. Switching molecule mid-treatment would mean changing provider.
What neither record tells you
Hims & Hers does not publish
- no tirzepatide price at 5, 7.5, 12.5, 15 mg per week
- no published twelve-month tirzepatide rate
LillyDirect (Zepbound) does not publish
- no published twelve-month tirzepatide rate
Ask Hims & Hers and LillyDirect (Zepbound) for each of those in writing before enrolling. A gap is not evidence of a problem; it does mean nothing can be checked against it.
What would change this answer
Evidence may be upgraded. Hims & Hers carries a price we have not captured at checkout. A capture would move the evidence term and could reorder these two without any price changing.
Which one suits which reader
On the lowest standing monthly rate for tirzepatide, LillyDirect (Zepbound) Official site wins this matchup. If you want to be able to pause without still paying, lillydirect (zepbound) carries no membership; and if you would rather trust a better-evidenced number, lillydirect (zepbound)'s price rests on stronger provenance.
Both figures should be checked at the provider's own checkout before you pay. Hims & Hers's tirzepatide price is reported as of 2026-08-11; LillyDirect (Zepbound)'s is verified as of 2026-08-11.
Questions
Is Hims & Hers or LillyDirect (Zepbound) cheaper for tirzepatide?
LillyDirect (Zepbound) is cheaper on all-in monthly cost at 10 mg/week: $449 against $697, a difference of $248 a month. All-in means the medication plus every mandatory recurring fee.
What is the twelve-month cost of Hims & Hers versus LillyDirect (Zepbound)?
Hims & Hers works out to $8,364 across twelve months and LillyDirect (Zepbound) to $5,388, on the plan terms each publishes.
Does Hims & Hers or LillyDirect (Zepbound) raise the price as the dose goes up?
Hims & Hers: yes, it prices by dose. LillyDirect (Zepbound): yes, it prices by dose. Where one program is flat and the other is tiered, the cheaper of the two can change as you titrate upward.
How many ways do Hims & Hers and LillyDirect (Zepbound) differ?
7 of the eight dimensions this site records: all-in monthly, twelve-month cost, dose policy, membership, shipping, commitment, cancellation terms and evidence status.
Which of Hims & Hers and LillyDirect (Zepbound) names its pharmacy?
Both do. Hims & Hers names Brand fulfillment (Wegovy, oral Wegovy, Zepbound) + partner pharmacy and LillyDirect (Zepbound) names Eli Lilly self-pay pharmacy (GiftHealth), so both can be checked against state board licensing and FDA inspection records.
How well evidenced are the Hims & Hers and LillyDirect (Zepbound) prices?
Hims & Hers's tirzepatide figure is reported — sourced from dated third-party reporting; first-party capture pending — captured 2026-08-11. LillyDirect (Zepbound)'s is verified, captured 2026-08-11. Evidence status is worth fifteen points in the Value Score, so it is priced in rather than mentioned as an aside.
Official sources: Hims & Hers official site · LillyDirect (Zepbound) official site. Compounded tirzepatide and semaglutide are not FDA-approved products.